Selenium Dioxide → HCID 20351772, compound

Participants

Reaction Steps

A solution of 9.3 g. of 5-chloro-2-hydroxymethylbenzhydrol in 50 ml. of acetic acid and 5.2 g. of selenium dioxide was refluxed for 3 hours. The mixture was filtered, cooled, poured on ice, made alkaline and extracted with ether. Concentration and addition of petroleum ether gave the product as prisms which after recrystallization from a mixture of ether and petroleum ether melted at 82°-84°. Ultraviolet maxima (2-propanol) at 230 mμ (ε = 19,500) and 257 mμ (ε = 23,500); infrared absorption (CHCl3) at 1675 cm-1 and 1705 cm-1.

Provenance & Evidence