1,3-Dichloropropane → HCID 21537970, compound

HRID 1579528Notes

Reaction equation

HRID 1579528 reaction equation
[NH2:1][C:2]1[C:10]([C:12]2[CH:17]=[CH:16][CH:15]=[CH:14][CH:13]=2)([OH:11])[C:9]2[C:4](=[CH:5][CH:6]=[C:7]([Cl:18])[CH:8]=2)[N:3]=1.Cl[CH2:20][CH2:21][CH2:22]Cl>>[Cl:18][C:7]1[CH:6]=[CH:5][C:4]2[N:3]3[CH2:20][CH2:21][CH2:22][N:1]=[C:2]3[C:10]([C:12]3[CH:17]=[CH:16][CH:15]=[CH:14][CH:13]=3)([OH:11])[C:9]=2[CH:8]=1

Participants

3

Reactant 2

HCID 88811,3-DichloropropaneHCID 2807151HCID 2807151, compound

Product 1

HCID 21537970HCID 21537970, compound

Procedure

Reaction of 2-amino-5-chloro-3-phenyl-3H-indol-3-ol (2.58 g) with 1,3-dichloropropane (1.1 g) according to the procedure of Example 1 step (c) gives the title compound as its hydrochloride salt, m.p. 279°-282°C (decomp).

Sources & evidence

ORD record
ord-cef78b2b4eea4b2faf8e02d83408e335
Source dataset
uspto-grants-1976_01
Patent number
US03931226

Reaction notes

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