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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 157954Generated: November 5, 2026

Tetrahydrofuran → 1-Boc-4-[Hydroxy-(4-trifluoromethoxyphenyl)methyl]piperidine

https://huagongshe.com/reaction/157954

Reaction equation

Participants

RoleNameHCIDCharge
ReactantTetrahydrofuranHCID 8028—
Reactant1-Bromo-4-(trifluoromethoxy)benzeneHCID 521008—
Reactanttert-Butyl 4-formylpiperidine-1-carboxylateHCID 1514430—
ReactantButyllithiumHCID 178418339—
Product1-Boc-4-[Hydroxy-(4-trifluoromethoxyphenyl)methyl]piperidineHCID 12052784—

Provenance & Evidence

DOI10.1039/C8SC04228D
Source datasetTraining data from https://doi.org/10.1039/C8SC04228D (9/10)
ORD IDord-817989c7f23f4215a833d614813a55af
Source noteTraining data from https://doi.org/10.1039/C8SC04228D (9/10)