Hydrogen Peroxide → 3-tert.-Butylsulfinyl-4-hydroxy-6-methyl-2-pyrone

Participants

Reaction Steps

Hydrogen peroxide (30%, 5.29 g., 0.467 mole) was added in one portion to a solution of 10.0 g. (0.0467 mole) of 3-tert.-butylthio-4-hydroxy-6-methyl-2-pyrone in 85 ml. of glacial acetic acid. The solution was allowed to stand at room temperature for 66 hours and then was poured into ice water, resulting in the precipitation of the pure product as 8.9 g. (83 percent) of white crystals, m.p. 119°C.

Provenance & Evidence