Sodium borohydride → HCID 21568992, compound

Participants

Reaction Steps

To a stirring solution of 34 g (0.15 mole) of 1-[5-(p-chlorophenyl)-2-furyl]-1-propanone in 300 ml of anhydrous methanol was added portionwise 4.1 g (0.11 mole) of NaBH4 while maintaining the temperature between 15°-20°. The reaction solution was stirred at room temperature for 3 hours and after standing over-night was added to ice/water with a solid forming. The solid was filtered and air-dried to yield 34 g (99%) of title compound. An analytical sample was prepared by recrystallizing a sample from hexane/charcoal, m.p. 74°-75°C.

Provenance & Evidence