HuagongsheHuagongshe Chemistry Print Report · For research reference only
Bromine → 4,5-dimethyl-6-oxo-7,8-dihydro-7-bromo-7-isopropyl-6H-indeno[5,4-b]furan-2-carboxylic acid
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Bromine | HCID 24408 | — |
| Reactant | 4,5-Dimethyl-6-oxo-7-isopropyl-7,8-dihydro-6H-indeno[5,4-b]furan-2-carboxylic acid | HCID 21568944 | — |
| Reactant | Sodium Bisulfite | HCID 23665763 | — |
| Catalyst | Hydrogen Bromide | HCID 260 | — |
| Solvent | Acetic Acid | HCID 176 | — |
| Product | 4,5-dimethyl-6-oxo-7,8-dihydro-7-bromo-7-isopropyl-6H-indeno[5,4-b]furan-2-carboxylic acid | HCID 21568958 | — |
Reaction Steps
A solution of 4,5-dimethyl-6-oxo-7,8-dihydro-7-isopropyl-6H-indeno[5,4-b]furan-2-carboxylic acid (0.01 mole) in acetic acid (60 ml.) is treated with 48% hydrobromic acid (1 drop) then with bromine (0.01 mole) in acetic acid (10 ml.) during a ten minute period. The solution is poured into ice water (300 ml.) containing sodium bisulfite (1 g.) to afford 4,5-dimethyl-6-oxo-7,8-dihydro-7-bromo-7-isopropyl-6-H-indeno[5,4-b]furan-2-carboxylic acid.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US03931239 |
| Source dataset | uspto-grants-1976_01 |
| ORD ID | ord-b35d7ec60ebc48a1a56d5a6be522bb76 |
| Source note | uspto-grants-1976_01 |