Water → HCID 53763309, compound

HRID 1579634Notes

Reaction equation

HRID 1579634 reaction equation
[CH3:1][C:2]1[C:10]2[O:11][C:12]([C:14]([OH:16])=[O:15])=[CH:13][C:9]=2[C:8]2[CH2:7][CH:6]([CH2:17][CH2:18][CH3:19])[C:5](=[O:20])[C:4]=2[C:3]=1[CH3:21].B(F)(F)F.[CH3:26][CH2:27]OCC.O>C(O)C>[CH3:1][C:2]1[C:10]2[O:11][C:12]([C:14]([O:16][CH2:26][CH3:27])=[O:15])=[CH:13][C:9]=2[C:8]2[CH2:7][CH:6]([CH2:17][CH2:18][CH3:19])[C:5](=[O:20])[C:4]=2[C:3]=1[CH3:21]

Participants

5

Reactant 3

HCID 962WaterHCID 8000Boron trifluoride etherateHCID 12741934HCID 12741934, compound

Product 1

HCID 53763309HCID 53763309, compound

Reagents, catalysts & solvents 1

HCID 702EthanolSolvent

Procedure

To a solution of 4,5-dimethyl-6-oxo-7-propyl-7,8-dihydro-6H-indeno[5,4-b]furan-2-carboxylic acid (8.0 g.) in ethanol (50 ml.) is added borontrifluoride etherate (13 ml.). The reaction mixture is refluxed for 0.5 hour, treated with water and cooled to afford ethyl [4,5-dimethyl-6-oxo-7-propyl-7,8-dihydro-6H-indeno[5,4-b]-furan-2-carboxylate] after filtration and drying.

Workup

  1. temperatureThe reaction mixture is refluxed for 0.5 hour
  2. temperaturecooled

Sources & evidence

ORD record
ord-1fc83b5e379f44bd88da9e65501122c3
Source dataset
uspto-grants-1976_01
Patent number
US03931239

Reaction notes

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