Sulfuric Acid → HCID 12741936, compound

Participants

Reaction Steps

A stirred suspension of 4,5-dimethyl-6-hydroxy-7-propyl-1,2,7,8-tetrahydro-6H-indeno[5,4-b]furan-2-carboxylic acid (5.0 g., 0.017 mole) in acetone (250 ml.) is treated over a ten minute period with an oxidizing reagent prepared from chromium trioxide (2.5 g. and concentrated sulfuric acid (2.2 ml.) in water (18 ml.). The acetone solution is decanted from the precipitated chromium salts and poured into water (700 ml.) affording 4,5-dimethyl-6-oxo-7-propyl-1,2,7,8-tetrahydro-6H-indeno-[5,4-b]furan-2-carboxylic acid which melts at 161°C. after recrystallization from butyl chloride.

Provenance & Evidence