HuagongsheHuagongshe Chemistry Print Report · For research reference only
Benzene → 4-[(2-Methyl-hydrazino)-methyl]-benzoic acid furfurylamide
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Benzene | HCID 241 | — |
| Reactant | Pyridine | HCID 1049 | — |
| Reactant | Furfurylamine | HCID 3438 | — |
| Reactant | 4-[(2-Methyl-1,2-dicarbobenzoxy-hydrazino)-methyl]-benzoyl chloride | HCID 21569059 | — |
| Catalyst | HCID 178418390 | HCID 178418390 | — |
| Solvent | Methanol | HCID 887 | — |
| Product | 4-[(2-Methyl-hydrazino)-methyl]-benzoic acid furfurylamide | HCID 54189965 | — |
Reaction Steps
By reaction of 23.4 g. of 4-[(2-methyl-1,2-dicarbobenzoxyhydrazino)-methyl]-benzoyl chloride with 4.85 g. of furfurylamine in a mixture of 8 ml. pyridine and 50 ml. of benzene according to the procedure of Example 4 above, followed by hydrogenolysis of the condensation product with palladium-carbon in methanol, there was obtained 4-[(2-methyl-hydrazino)-methyl]-benzoic acid furfurylamide, the oxalate of which melted at 170°-171° (dec.).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US03931268 |
| Source dataset | uspto-grants-1976_01 |
| ORD ID | ord-3f7227782f1943e9a37bf14159e53e62 |
| Source note | uspto-grants-1976_01 |