Water → Methyl phenylacetate

Participants

Reaction Steps

To a solution of the above lactone in 45 ml. of toluene at -78° C. is added dropwise, while stirring, diisobutylaluminum hydride (3.9 ml.). Stirring is continued at -78° C. for 0.5 hr., whereupon a solution of 9 ml. of water in 17 ml. of tetrahydrofuran is added. After the mixture is stirred for an additional hour at about 25° C. it is filtered. The filtrate is washed with brine, dried, and concentrated to yield the formula-LXXII title compound, 4.39 g., on oil.

Provenance & Evidence