HCID 54466372, compound → HCID 54015699, compound

Participants

Reaction Steps

A mixture of 5.35 g of the said ester in 50 ml of methanol and 20 ml of 2N sodium hydroxide were refluxed for 2 hours and then the methanol was distilled off. The mixture was added to water, treated with activated carbon and filtered. The filtrate was acidified with 3 ml of concentrated hydrochloric acid and was extracted with ether. The ether extract was washed with water until the wash water was neutral, dried over sodium sulfate and evaporated to dryness under reduced pressure to obtain 4.31 g of 4-(m-benzoyl-phenyl)-4-methyl-3-butenoic acid.

Provenance & Evidence