Diethyl Ether → HCID 11137439, compound

HRID 1579823Notes

Reaction equation

HRID 1579823 reaction equation
CCOCC.C(C(C)=O)C.[CH3:11][C:12](O)([CH2:15][C:16]1[CH:21]=[CH:20][C:19]([CH3:22])=[CH:18][CH:17]=1)[CH2:13][CH3:14]>O>[CH3:11][CH:12]([CH2:15][C:16]1[CH:21]=[CH:20][C:19]([CH3:22])=[CH:18][CH:17]=1)[CH:13]=[CH2:14]

Participants

5

Reactant 3

HCID 3283Diethyl EtherHCID 6569Methyl Ethyl KetoneHCID 21569570HCID 21569570, compound

Product 1

HCID 11137439HCID 11137439, compound

Reagents, catalysts & solvents 1

HCID 962WaterSolvent

Procedure

was obtained from 0.77 mol of metallic magnesium and 0.59 mol of p-methyl benzyl chloride. To this was added 0.6 mol of an ether solution of methyl ethyl ketone. After thorough reaction, a large excess of water was added to hydrolyze the reaction product. The resulting 3-methyl-4-(p-tolyl)-3-butanol was passed through a reaction tube packed with active alumina at 200° to 300°C. to afford the desired 3-methyl-4-(p-tolyl) butene almost quantitatively.

Workup

  1. customAfter thorough reaction
  2. custompacked with active alumina at 200° to 300°C.

Sources & evidence

ORD record
ord-17351694e6ab4bcea9c8cccd51a1eddd
Source dataset
uspto-grants-1976_01
Patent number
US03931348

Reaction notes

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