Isopropylamine → HCID 21569109, compound

HRID 1579830Notes

Reaction equation

HRID 1579830 reaction equation
[CH3:1][O:2][C:3]1[CH:4]=[C:5]2[C:10](=[CH:11][CH:12]=1)[CH:9]=[C:8]([CH:13]([OH:19])[C:14]([O:16]CC)=O)[CH:7]=[CH:6]2.[CH:20]([NH2:23])([CH3:22])[CH3:21]>>[CH:20]([NH:23][C:14](=[O:16])[CH:13]([C:8]1[CH:7]=[CH:6][C:5]2[C:10](=[CH:11][CH:12]=[C:3]([O:2][CH3:1])[CH:4]=2)[CH:9]=1)[OH:19])([CH3:22])[CH3:21]

Participants

3

Reactant 2

HCID 6363IsopropylamineHCID 21569133HCID 21569133, compound

Product 1

HCID 21569109HCID 21569109, compound

Procedure

Ethyl 6-methoxy-2-naphthylglycolate (0.1 mole) is stirred with 20 ml. of isopropylamine at about 35°C with stirring overnight and the temperature is then raised to reflux for 28 hours. The reaction mixture is evaporated in vacuo and the residue distilled to obtain N-isopropyl-6-methoxy-2-naphthylglycolamide.

Workup

  1. temperaturethe temperature is then raised
  2. temperatureto reflux for 28 hours
  3. customThe reaction mixture is evaporated in vacuo
  4. distillationthe residue distilled

Sources & evidence

ORD record
ord-fb185d3279d347b8b4c1208aa874850c
Source dataset
uspto-grants-1976_01
Patent number
US03931269

Reaction notes

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