HCID 21137946, compound → HCID 21569128, compound

HRID 1579839Notes

Reaction equation

HRID 1579839 reaction equation
[C:1]([S-:4])(=[S:3])[CH3:2].[Na+].Cl[CH:7]([C:13]1[CH:22]=[CH:21][C:20]2[C:15](=[CH:16][CH:17]=[C:18]([O:23][CH3:24])[CH:19]=2)[CH:14]=1)[C:8]([O:10][CH2:11][CH3:12])=[O:9]>C(O)C>[C:1]([S:4][CH:7]([C:13]1[CH:22]=[CH:21][C:20]2[C:15](=[CH:16][CH:17]=[C:18]([O:23][CH3:24])[CH:19]=2)[CH:14]=1)[C:8]([O:10][CH2:11][CH3:12])=[O:9])(=[S:3])[CH3:2]

Participants

4

Reactant 2

HCID 21137946HCID 21137946, compoundHCID 21569131HCID 21569131, compound

Product 1

HCID 21569128HCID 21569128, compound

Reagents, catalysts & solvents 1

HCID 702EthanolSolvent

Procedure

A mixture of 0.2 moles of sodium dithioacetate and 0.12 moles of ethyl α-chloro-6-methoxy-2-naphthylacetate in 300 ml. of absolute ethanol is stirred at room temperature for 15 hours. The reaction mixture is filtered, washed with absolute ethanol and evaporated to dryness in vacuo. The residue is treated with ether, filtered and evaporated to dryness to obtain ethyl α-thioacetylthio-6-methoxy-2-naphthylacetate.

Workup

  1. filtrationThe reaction mixture is filtered
  2. washwashed with absolute ethanol
  3. customevaporated to dryness in vacuo
  4. additionThe residue is treated with ether
  5. filtrationfiltered
  6. customevaporated to dryness

Sources & evidence

ORD record
ord-f8966961936045e3bfea9579edd4f25e
Source dataset
uspto-grants-1976_01
Patent number
US03931269

Reaction notes

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