HuagongsheHuagongshe Chemistry Print Report · For research reference only
Dimethylcarbamoyl Chloride → alpha-Diethylcarbamylthio-6-methoxy-2-naphthylacetic acid
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Dimethylcarbamoyl Chloride | HCID 6598 | — |
| Reactant | Diethylcarbamoyl chloride | HCID 6916 | — |
| Reactant | Carbamic chloride | HCID 68048 | — |
| Reactant | N-ethylcarbamoyl chloride | HCID 12321963 | — |
| Reactant | alpha-Carbamylthio-6-methoxy-2-naphthylacetic acid | HCID 21569102 | — |
| Reactant | alpha-Dimethylcarbamylthio-6-methoxy-2-naphthylacetic acid | HCID 21569125 | — |
| Reactant | alpha-Ethylcarbamylthio-6-methoxy-2-naphthylacetic acid | HCID 86732901 | — |
| Product | alpha-Diethylcarbamylthio-6-methoxy-2-naphthylacetic acid | HCID 21569122 | — |
Reaction Steps
When diethylcarbamylchloride is replaced in the above procedure by carbamyl chloride (prepared in situ from potassium cyanate and anhydrous hydrogen chloride in anhydrous chloroform), ethylcarbamyl chloride or dimethylcarbamyl chloride, then the products prepared are α-carbamylthio-6-methoxy-2-naphthylacetic acid, α-ethylcarbamylthio-6-methoxy-2-naphthylacetic acid or α-dimethylcarbamylthio-6-methoxy-2-naphthylacetic acid.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US03931269 |
| Source dataset | uspto-grants-1976_01 |
| ORD ID | ord-223595e68bfe40c3bf6bc68e0ad04983 |
| Source note | uspto-grants-1976_01 |