Isobutyric anhydride → Methylene bisisobutyrate

참여 물질

반응 단계

A 30-g (0.33 mol) sample of trioxane was added to a solution of 158 g (1 mol) isobutyric anhydride and 0.5 ml 70 percent perchloric acid over a 30-minute period at 65°-70°C. The reaction mixture was then stirred until the temperature decreased to 27°C. The reaction mixture was diluted with saturated sodium bicarbonate solution and extracted with ether. The ether extracts were dried over magnesium sulfate and evaporated under reduced pressure. The resulting residue was distilled on a 30-cm column to give 112 g of methylene bisisobutyrate, b.p. 43°-48°C. at 0.2-0.3 mm of Hg and 30 g of oxybismethylene isobutyrate, b.p. 57°-63°C. at 0.2-0.3 mm of Hg.

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