p-Toluenesulfonic acid → HCID 21569624, compound

Participants

Reaction Steps

A mixture of 2.6 g. (0.01 mole) of 2-phenacyl-1-tetralone, 2.3 g. (0.01 mole) of dimethylphosphinylmethyl p-aminobenzoate, 0.4 g. of p-toluenesulfonic acid, and 250 ml. of dry toluene was heated under reflux for 73 hours, concentrated to about 100 ml., diluted with 25 ml. of cyclohexane, and cooled. The solid which separated was collected to provide 2.6 g. (57%) of solid, m.p. 171°-173°. Recrystallization from cyclohexane-benzene gave pale yellow crystals, m.p. 180°-181°.

Provenance & Evidence