反应详情

A stirred mixture of 15.9 g. (0.11 mole) of 1-pyrrolidino-1-cyclohexene, 28.0 g. (0.11 mole) of m-trifluoromethylphenacyl bromide, and 100 ml. of toluene was heated under reflux for 2 hours, diluted with water and refluxed for 2 hours. The layers were separated, and the organic phase was dried and concentrated to 25 g. of liquid. Distillation provided 12.0 g. (42%) of liquid, b.p. 137°-138° (0.075 mm.).

1. additionA stirred mixture of 15.9 g
2. temperatureunder reflux for 2 hours
3. temperaturerefluxed for 2 hours
4. customThe layers were separated
5. customthe organic phase was dried
6. concentrationconcentrated to 25 g
7. distillationDistillation
8. customprovided 12.0 g