HuagongsheHuagongshe Chemistry Print Report · For research reference only
5-Aminosalicylic Acid → HCID 12270289, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 5-Aminosalicylic Acid | HCID 4075 | — |
| Reactant | Cyclohexanone, 2-[2-(4-methoxyphenyl)-2-oxoethyl]- | HCID 12270325 | — |
| Solvent | Acetic Acid | HCID 176 | — |
| Product | HCID 12270289 | HCID 12270289 | — |
Reaction Steps
A mixture of 24.6 g. (0.1 mole) of 2-(p-methoxyphenacyl)cyclohexanone, 15.3 g. (0.1 mole) of 5-aminosalicylic acid, and 100 ml. of glacial acetic acid was heated under reflux for 3 hours, cooled and filtered. The filter cake was washed with water, dried and recrystallized from ethanol to provide 14.4 g. (40%) of crystals, m.p. 219°-221°.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US03931407 |
| Source dataset | uspto-grants-1976_01 |
| ORD ID | ord-c998fef5b3f543c8869245267a058a79 |
| Source note | uspto-grants-1976_01 |