HuagongsheHuagongshe Chemistry Print Report · For research reference only
5-Aminosalicylic Acid → HCID 12270294, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 5-Aminosalicylic Acid | HCID 4075 | — |
| Reactant | Cyclohexanone, 2-[2-(4-bromophenyl)-2-oxoethyl]- | HCID 12270330 | — |
| Solvent | Acetic Acid | HCID 176 | — |
| Product | HCID 12270294 | HCID 12270294 | 19.2% |
Reaction Steps
A mixture of 44.3 g. (0.15 mole) of 2-(p-bromophenacyl)cyclohexanone, 23.0 g. (0.15 mole) of 5-aminosalicylic acid, and 115 ml. of glacial acetic acid was heated under reflux for 2 hours, cooled and filtered. The filter cake was washed with water, dried and recrystallized from acetic acid to provide 11.9 g (19%) of tan crystals, m.p. 231°-232°.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US03931407 |
| Source dataset | uspto-grants-1976_01 |
| ORD ID | ord-cf4ebee0016c477aa80070a94625925c |
| Source note | uspto-grants-1976_01 |