HuagongsheHuagongshe Chemistry Print Report · For research reference only
5-Aminosalicylic Acid → HCID 12270297, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 5-Aminosalicylic Acid | HCID 4075 | — |
| Reactant | Cyclohexanone, 2-[2-(4-hydroxyphenyl)-2-oxoethyl]- | HCID 12270333 | — |
| Solvent | Acetic Acid | HCID 176 | — |
| Product | HCID 12270297 | HCID 12270297 | — |
Reaction Steps
A mixture of 11.5 g. (0.05 mole) of 2-(p-hydroxyphenacyl)cyclohexanone, 7.6 g. (0.05 mole) of 5-aminosalicylic acid, and 40 ml. of glacial acetic acid was heated under reflux under nitrogen for 1.5 hours, cooled and filtered to provide 10.6 g. (61%) of solid, m.p. 214°-217°. Recrystallization from acetonitrile gave crystals, m.p. 217°-219°.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US03931407 |
| Source dataset | uspto-grants-1976_01 |
| ORD ID | ord-73567ef441ca489ca586a551a5cd9df0 |
| Source note | uspto-grants-1976_01 |