HuagongsheHuagongshe Chemistry Print Report · For research reference only
Hydrochloric Acid → 5-{3-[4-(2-methylphenyl)-1-piperazinyl]-propoxy}-3,4-dihydro-2H-naphthalene-1-one
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Hydrochloric Acid | HCID 313 | — |
| Reactant | 5-Hydroxy-1-tetralone | HCID 119921 | — |
| Reactant | 1-(3-Chloropropyl)-4-(2-methylphenyl)piperazine | HCID 233671 | — |
| Product | 5-{3-[4-(2-methylphenyl)-1-piperazinyl]-propoxy}-3,4-dihydro-2H-naphthalene-1-one | HCID 21564739 | 73.4% |
Reaction Steps
from 5-hydroxy-1-oxotetraline and 1-(3-chloropropyl)-4 -(2-methylphenyl)-piperazine; yield 73.4% of theory; m.p. of the hydrochloride (recrystallized from water) 243°-245°C;
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US03932411 |
| Source dataset | uspto-grants-1976_01 |
| ORD ID | ord-07ff413292404d1faf3e7faf3af403a1 |
| Source note | uspto-grants-1976_01 |