HCID 21426389, compound → HCID 178492682, compound

Participants

Reaction Steps

4-Methoxy-8-nitroquinaldic acid (3.6 g) (see Example 16) and N,N'-carbonyldiimidazole (2.5 g) in dimethylformamide (70 ml) were heated on a steam bath for 1 hour. 5-Aminotetrazole (2.5 g) was added and the mixture was heated on a steam bath for 1 hour and cooled. 4-Methoxy-8-nitro-N(1H-tetrazol-5-yl)quinaldamide, compound with imidazole, m.p. 238°, was filtered off and was triturated with 2N hydrochloric acid (50 ml). 4-Methoxy-8-nitro-N(1H-tetrazol-5-yl)quinaldamide was collected and dried, m.p. 268° (d).

Provenance & Evidence