Methyl isothiocyanate → HCID 20316739, compound

Participants

Reaction Steps

A solution of 2-(3-aminopropylamino)pyridine (2.74 g.) and methyl isothiocyanate (1.46 g.) in isopropyl alcohol (50 ml.) was stirred at room temperature for 16 hours. Concentration, followed by trituration of the residue under methyl ethyl ketone gave the crude product which was recrystallised from aqueous ethanol to give N-methyl-N'-[3-(2-pyridylamino)propyl]thiourea (2,45 g.), m.p. 134°-135°. (Found: C, 53.4; H, 7.2; N, 25.0; S, 14.3. C10H16N4S requires: C, 53.5; H, 7.2; N, 25.0; S, 14.3).

Provenance & Evidence