反应详情

A mixture of 15.5 g (0.05 mole) of N-ethyl-3,6-carbazolediol diacetate, 17.2 g (0.1 mole) of 2-diethylaminoethylchloride hydrochloride, 10.8 g (0.2 mole) of sodium methoxide and 400 ml. of chlorobenzene was refluxed for 24 hours. Upon cooling, the reaction mixture was filtered, and the filtrate was washed with several portions of water, dried over anhydrous magnesium sulfate, diluted with ether and acidified with ethereal HCl. The resulting precipitate was separated and recrystallized from methanol-ethyl acetate to give the desired product. M.P. 208°-210°C, λmaxEtOH 232, E1cm1% 853.

1. temperatureUpon cooling
2. filtrationthe reaction mixture was filtered
3. washthe filtrate was washed with several portions of water
4. dry with materialdried over anhydrous magnesium sulfate
5. additiondiluted with ether
6. customThe resulting precipitate was separated
7. customrecrystallized from methanol-ethyl acetate