HuagongsheHuagongshe Chemistry Print Report · For research reference only
Chloroacetamide → HCID 21767161, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Chloroacetamide | HCID 6580 | — |
| Reactant | Potassium Carbonate | HCID 11430 | — |
| Reactant | Potassium Hydroxide | HCID 14797 | — |
| Reactant | 4-(Diethylamino)-2-hydroxybenzaldehyde | HCID 87293 | — |
| Solvent | Dimethylformamide | HCID 6228 | — |
| Product | HCID 21767161 | HCID 21767161 | 68% |
Reaction Steps
When 4-diethylaminosalicylaldehyde is reacted with chloroacetamide and potassium hydroxide in dimethylformamide at ambient temperature or with potassium carbonate instead of potassium hydroxide at refluxing temperature, the above benzofuran derivative is obtained in a similarly good yield.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US03932446 |
| Source dataset | uspto-grants-1976_01 |
| ORD ID | ord-ac9487a51efd4df4be4fc273b0a9ba0a |
| Source note | uspto-grants-1976_01 |