Benzoyl chloride → HCID 12286684, compound

Participants

Reaction Steps

0.35 g of 1-(3-hydroxyphenyl)-6,7-dimethyl-6-azabicyclo [3,2,1]octane is dissolved in 4 ml of pyridine, and a solution of 0.28 g of benzoyl chloride in 2 ml of benzene is added thereto under ice-cooling. The mixture is stirred for 45 minutes. Then, the mixture is concentrated under reduced pressure. The residue thus obtained is washed with ether and then recrystallized from a mixture of ethylacetate and acetone. 0.43 g of 1-(3-benzoyloxyphenyl)-6,7-dimethyl-6-azabicyclo[3,2,1]octane hydrochloride is obtained. M.p. 207° - 209°C.

Provenance & Evidence