Ethanol → HCID 178424053, compound

HRID 1580158Notes

Reaction equation

HRID 1580158 reaction equation
[C:1]1([CH3:19])[CH:6]=[CH:5][C:4]([C:7]([CH:9]2[CH2:17][C:16]3[C:11](=[CH:12][CH:13]=[CH:14][CH:15]=3)[C:10]2=O)=O)=[CH:3][CH:2]=1.C(O)C.[NH2:23][NH2:24]>C(Cl)(Cl)Cl>[C:1]1([CH3:19])[CH:6]=[CH:5][C:4]([C:7]2[NH:24][N:23]=[C:10]3[C:11]4[C:16]([CH2:17][C:9]=23)=[CH:15][CH:14]=[CH:13][CH:12]=4)=[CH:3][CH:2]=1

Participants

5

Reactant 3

HCID 702EthanolHCID 9321HydrazineHCID 12272532HCID 12272532, compound

Product 1

HCID 178424053HCID 178424053, compound

Reagents, catalysts & solvents 1

HCID 6212ChloroformSolvent

Procedure

To a warm solution of 3.3 g. of the diketone of Step A in 33 ml. of ethanol and 10 ml. of chloroform is added 4 g. of hydrazine and the resulting solution is refluxed for 1 hr. It is then cooled and evaporated to dryness under reduced pressure. The crude solid residue obtained is crystallized from methanol to yield the product 3-(p-tolyl)-4H-indeno[1,2-c]-pyrazole (m.p. 250°-252°C).

Workup

  1. temperatureIt is then cooled
  2. customevaporated to dryness under reduced pressure
  3. customThe crude solid residue obtained
  4. customis crystallized from methanol

Sources & evidence

ORD record
ord-cbba8349ada5414c815fb63a2b7aa74e
Source dataset
uspto-grants-1976_01
Patent number
US03932430

Reaction notes

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