2-Methyl-3-(4-pyridyl)-3,3A,4,5-tetrahydro-2H-benz(G)indazole → 2-Methyl-3-pyridin-4-yl-4,5-dihydrobenzo[g]indazole

HRID 1580160Notes

Reaction equation

HRID 1580160 reaction equation
[CH3:1][O:2][C:3]1[CH:22]=[CH:21][C:6]2[CH2:7][CH2:8][CH2:9][CH:10]3[CH:14]([C:15]4[CH:20]=[CH:19][N:18]=[CH:17][CH:16]=4)[NH:13][N:12]=[C:11]3[C:5]=2[CH:4]=1.[CH3:23][N:24]1[CH:28]([C:29]2[CH:34]=[CH:33][N:32]=[CH:31][CH:30]=2)[CH:27]2[CH2:35][CH2:36][C:37]3[C:42]([C:26]2=[N:25]1)=[CH:41][CH:40]=[CH:39][CH:38]=3>>[CH3:1][O:2][C:3]1[CH:22]=[CH:21][C:6]2[CH2:7][CH2:8][CH2:9][C:10]3[C:11](=[N:12][NH:13][C:14]=3[C:15]3[CH:20]=[CH:19][N:18]=[CH:17][CH:16]=3)[C:5]=2[CH:4]=1.[CH3:23][N:24]1[C:28]([C:29]2[CH:30]=[CH:31][N:32]=[CH:33][CH:34]=2)=[C:27]2[CH2:35][CH2:36][C:37]3[C:42]([C:26]2=[N:25]1)=[CH:41][CH:40]=[CH:39][CH:38]=3

Participants

4

Reactant 2

HCID 35654222-Methyl-3-(4-pyridyl)-3,3A,4,5-tetrahydro-2H-benz(G)indazoleHCID 215649539-Methoxy-3-(4-pyridyl)-2,3,3a,4,5,6-hexahydrobenzo[6,7]cyclohepta[1,2-c] pyrazole

Product 2

HCID 3172122-Methyl-3-pyridin-4-yl-4,5-dihydrobenzo[g]indazoleHCID 178487043HCID 178487043, compound

Procedure

Following the above procedure but using an equivalent amount of 9-methoxy-3-(4-pyridyl)-2,3,3a,4,5,6-hexahydrobenzo[6,7]cyclohepta[1,2-c] pyrazole or 2-methyl-3-(4-pyridyl)-3,3a,4,5-tetrahydro-2H-naphtho[1,2-c] pyrazole in place of the 3-(4-pyridyl)-2,3,3a,4,5,6-hexahydrobenzo[6,7]cyclohepta[ 1,2-c]pyrazole used therein, there is obtained 9-methoxy-3-(4-pyridyl)-2,4,5,6-tetrahydrobenzo[ 6,7]cyclohepta[1,2-c]pyrazole (m.p. 200°-201°C) or 2-methyl-3-(4-pyridyl)-4,5-dihydro-2H-naphtho[1,2-c]pyrazole (m.p. 124°-217°C).

Sources & evidence

ORD record
ord-abea8a5120ef4069b33571b57678dcb8
Source dataset
uspto-grants-1976_01
Patent number
US03932430

Reaction notes

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