HuagongsheHuagongshe Chemistry Print Report · For research reference only
Piperidine → 2-(Pyridin-4-ylmethylidene)-3,4-dihydronaphthalen-1-one
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Piperidine | HCID 8082 | — |
| Reactant | 1-Tetralone | HCID 10724 | — |
| Reactant | 4-Pyridinecarboxaldehyde | HCID 13389 | — |
| Solvent | Acetic Acid | HCID 176 | — |
| Product | 2-(Pyridin-4-ylmethylidene)-3,4-dihydronaphthalen-1-one | HCID 2732716 | — |
Reaction Steps
A mixture of 73.0 grams (0.50 moles) of α-tetralone, 64.2 grams (0.60 moles) of 4-pyridinecarboxaldehyde, 10 grams of piperidine and 10 grams of acetic acid are heated at 80° for 19 hours. The resultant solid is crystallized from about 400 ml. of ethanol to give 2-(4-pyridylmethylene)- 1-tetralone; (m.p. 112°-114°C).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US03932430 |
| Source dataset | uspto-grants-1976_01 |
| ORD ID | ord-40b25525dc954f0f82aa11e588b440a5 |
| Source note | uspto-grants-1976_01 |