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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1580241Generated: November 4, 2026

Nitric Acid → 2,5-Cyclohexadiene-1,4-dione, 2,3,5-trimethyl-

https://huagongshe.com/reaction/1580241

Reaction equation

Participants

RoleNameHCIDCharge
ReactantNitric AcidHCID 944—
Reactant2,3,6-TrimethylphenolHCID 17016—
CatalystSodium NitriteHCID 23668193—
SolventAcetic AcidHCID 176—
Product2,5-Cyclohexadiene-1,4-dione, 2,3,5-trimethyl-HCID 7029169.6%

Reaction Steps

Also, in the process described in Japanese Pat. Publication No. 38063/70 (German Pat. OLS No. 1,814,652), 2,3,6-trimethylphenol is dissolved in acetic acid and oxidized with a dilute nitric acid using sodium nitrite as a catalyst to obtain trimethyl-p-benzoquinone in maximum yield of 69.6 percent. This process is simple and is considered to be a good one. However, the yield is a little low.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS03932475
Source datasetuspto-grants-1976_01
ORD IDord-03c3211cbb2a4164b7eb9990a21a3510
Source noteuspto-grants-1976_01