反应详情

By procedures similar to those described in Example 1, ethyl 2-(2,4'-difluoro-4-biphenylyl)-2-methylmalonate was hydrolysed and the resulting crude 2-(2,4'-difluoro-4-biphenylyl)-2-methylmalonic acid was decarboxylated to give 2-(2,4'-difluoro-4-biphenylyl)-propionic acid, m.p. 118°-119°C.