Benzylamine → HCID 21566268, compound

HRID 1580291Notes

Reaction equation

HRID 1580291 reaction equation
[F:1][C:2]1[CH:7]=[C:6]([F:8])[CH:5]=[CH:4][C:3]=1[C:9]1[CH:14]=[CH:13][C:12]([CH:15]([CH3:19])[C:16]([OH:18])=[O:17])=[CH:11][CH:10]=1.[CH2:20]([NH2:27])[C:21]1[CH:26]=[CH:25][CH:24]=[CH:23][CH:22]=1>CCOCC>[F:1][C:2]1[CH:7]=[C:6]([F:8])[CH:5]=[CH:4][C:3]=1[C:9]1[CH:14]=[CH:13][C:12]([CH:15]([CH3:19])[C:16]([OH:18])=[O:17])=[CH:11][CH:10]=1.[CH2:20]([NH2:27])[C:21]1[CH:26]=[CH:25][CH:24]=[CH:23][CH:22]=1

Participants

4

Reactant 2

HCID 7504BenzylamineHCID 21566267HCID 21566267, compound

Product 1

HCID 21566268HCID 21566268, compound

Reagents, catalysts & solvents 1

HCID 3283Diethyl EtherSolvent2×

Procedure

2-(2',4'-Difluoro-4-biphenylyl)propionic acid (0.5 g.) in ether (25 ml.) was mixed with benzylamine (0.204 g.) in ether (5 ml.). The resulting precipitate was collected, washed with water and dried in vacuo to give benzylamine 2-(2',4'-difluoro-4-biphenylyl)propionate, m.p. 148°-150°C.

Workup

  1. customThe resulting precipitate was collected
  2. washwashed with water
  3. customdried in vacuo

Sources & evidence

ORD record
ord-06dc42483df341f9aaf2619e5d6c8cf3
Source dataset
uspto-grants-1976_01
Patent number
US03932499

Reaction notes

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