反应详情

2-(2,4'-Difluoro-4-biphenylyl)propionic acid (830 mg.), ethanol (10 ml.) and concentrated sulphuric acid (0.5 ml.) were refluxed for 16 hours. The solution was diluted with ice-water (200 ml.) and extracted with ether. After the usual washing, evaporation of the ether and distillation of the residue gave ethyl 2-(2,4'-difluoro-4-biphenylyl)-propionate, b.p. 145°-146°C./0.8 mm.

1. extractionextracted with ether
2. customAfter the usual washing, evaporation of the ether and distillation of the residue