HuagongsheHuagongshe Chemistry Print Report · For research reference only
Bromide ion → 1-Bromo-5,5-dimethyl-3-tetrahydropyranyloxy-trans-1-octene
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Bromide ion | HCID 259 | — |
| Reactant | Bis(1,2-dimethylpropyl)borane | HCID 192733 | — |
| Reactant | 5,5-Dimethyl-3-tetrahydropyranyloxy-1-octyne | HCID 53889730 | — |
| Solvent | Carbon Tetrachloride | HCID 5943 | — |
| Product | 1-Bromo-5,5-dimethyl-3-tetrahydropyranyloxy-trans-1-octene | HCID 86732973 | — |
Reaction Steps
Treatment of 7.15 g. (30 moles) of 5,5-dimethyl-3-tetrahydropyranyloxy-1-octyne (Example 999) with 33 moles of disiamylborane in carbon tetrachloride followed by 30 moles of bromide in carbon tetrachloride, refluxing the resulting mixture, and isolation by chromatography on silica gel, all as described in Example 1173 gives the title compound.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US03932479 |
| Source dataset | uspto-grants-1976_01 |
| ORD ID | ord-5a7b2f9318414eaa8cee6f728e64af1b |
| Source note | uspto-grants-1976_01 |