2-Tert-Butylphenol → 4-tert-Butylphenol

HRID 1580418Notes

Reaction equation

HRID 1580418 reaction equation
[C:1]([C:5]1[CH:10]=[CH:9][CH:8]=[CH:7][C:6]=1O)([CH3:4])([CH3:3])[CH3:2].C1(S(O)(=O)=O)C=CC=C(S(O)(=O)=[O:19])C=1>>[C:1]([C:5]1[CH:10]=[CH:9][C:8]([OH:19])=[CH:7][CH:6]=1)([CH3:4])([CH3:3])[CH3:2]

Participants

3

Reactant 2

HCID 69232-Tert-ButylphenolHCID 7388Benzene-1,3-disulfonic acid

Product 1

HCID 73934-tert-ButylphenolYield 84%

Conditions

Temperature
150 °C

Procedure

Two grams of ortho-tertiary-butyl phenol was mixed with 1% of meta-benzenedisulfonic acid and heated in a test tube for 1.5 hours with occasional stirring at 150°C. Analysis gave 84.0% para-tertiary-butyl phenol; the remaining components consisted of its isomers.

Workup

  1. temperatureheated in a test tube for 1.5 hours

Sources & evidence

ORD record
ord-e483feba7a094624acf2c02427ba3b48
Source dataset
uspto-grants-1976_01
Patent number
US03932537

Reaction notes

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