Acetic Anhydride → HCID 54347407, compound

HRID 1580523Notes

Reaction equation

HRID 1580523 reaction equation
[C:1]1([C:23]2[CH:28]=[CH:27][CH:26]=[CH:25][CH:24]=2)[CH:6]=[CH:5][C:4]([C:7]([C:11]2[CH:16]=[CH:15][C:14]([C:17]3[CH:22]=[CH:21][CH:20]=[CH:19][CH:18]=3)=[CH:13][CH:12]=2)=[CH:8][CH2:9][NH2:10])=[CH:3][CH:2]=1.[C:29](OC(=O)C)(=[O:31])[CH3:30]>C(O)(=O)C>[C:14]1([C:17]2[CH:22]=[CH:21][CH:20]=[CH:19][CH:18]=2)[CH:15]=[CH:16][C:11]([C:7]([C:4]2[CH:3]=[CH:2][C:1]([C:23]3[CH:24]=[CH:25][CH:26]=[CH:27][CH:28]=3)=[CH:6][CH:5]=2)=[CH:8][CH2:9][NH:10][C:29](=[O:31])[CH3:30])=[CH:12][CH:13]=1

Participants

4

Reactant 2

HCID 7918Acetic AnhydrideHCID 20363851HCID 20363851, compound2×

Product 1

HCID 54347407HCID 54347407, compound

Reagents, catalysts & solvents 1

HCID 176Acetic AcidSolvent

Procedure

1, 1 - di (4 - biphenylyl) -3 - amino - prop -1 -ene (1g) was added to a mixture of anhydrous sodium acetate (1g), acetic acid (10 ml) and acetic anhydride (1 ml) and the mixture was refluxed for one hour then evaporated in vacuo. The residue was washed with water and dried and recrystallised from n - propanol to give 1, 1- di (4-biphenylyl) -3 - acetamido - prop -1 - ene. (m.p. 246°- 249°C). This compound was reduced in a similar manner to the method described in Example 43 to yield 1, 1 - di (4-biphenylyl) -3 - ethylamino - prop -1 - ene.

Workup

  1. temperaturethe mixture was refluxed for one hour
  2. customthen evaporated in vacuo
  3. washThe residue was washed with water
  4. customdried
  5. customrecrystallised from n - propanol

Sources & evidence

ORD record
ord-0f8b5e3e98b44c5cb33571962d4a6a50
Source dataset
uspto-grants-1976_01
Patent number
US03932663

Reaction notes

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