HuagongsheHuagongshe Chemistry Print Report · For research reference only
Hydrochloric Acid → Aspartame
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Hydrochloric Acid | HCID 313 | — |
| Reactant | Methanol | HCID 887 | — |
| Reactant | L-Aspartyl-L-phenylalanine | HCID 93078 | — |
| Product | Aspartame | HCID 134601 | — |
Reaction Steps
A solution of 1.86 g. of α-L-aspartyl-L-phenylalanine, 2.9 ml. of 2.6 N hydrochloric acid in methanol and 7.2 ml. of methanol was stirred at 30°C. for 2 hours. The resulting yields, based on the initial charge of α-L-aspartyl-L-phenylalanine, are as follows (by TLC):
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US03933781 |
| Source dataset | uspto-grants-1976_01 |
| ORD ID | ord-85e7a227f1444ab2a8e6a4b216bc68a2 |
| Source note | uspto-grants-1976_01 |