Water → HCID 21562987, compound

Participants

Reaction Steps

2-p-Nitrobenzoylthiophene (2.33 g.) was allowed to react with potassium cyanide (3.9 g., 6 mols) in dimethyl sulphoxide (40 ml.) at 100°C for 31/2 hours. The solution was poured into water and the cloudiness removed with charcoal. The clear filtrate gave a precipitate on acidification; this was collected and crystallised from aqueous ethanol to give 2-(3-cyano-4-hydroxybenzoyl)thiophene, m.p. 216°C.

Provenance & Evidence