참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|
| 반응물 | 3-(Trifluoromethyl)aniline | HCID 7375 | — |
| 반응물 | Sodium Methoxide | HCID 10942334 | — |
| 반응물 | HCID 178418361 | HCID 178418361 | — |
| 촉매 | Ruthenium | HCID 23950 | — |
| 용매 | 1,4-Dioxane | HCID 31275 | — |
| 생성물 | 3-(Trifluoromethyl)cyclohexylamine (cis-and trans-mixture) | HCID 16227766 | — |
반응 단계
A mixture of 200 parts of 3-aminobenzotrifluoride, 4 parts of sodium methoxide, 15 parts of 5% ruthenium on alumina, and 200 parts of dioxane is heated in an autoclave at 175°C. under 5,000 p.s.i. of hydrogen for 4 hours. The reaction mixture is cooled and filtered and the solvent is evaporated in a rotary evaporator. The residue is distilled to give 159 parts of 3-trifluoromethylcyclohexylamine, b.p. 69°-70°/27 mm.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|
| 특허 번호 | US03933815 |
|---|
| 출처 데이터셋 | uspto-grants-1976_01 |
|---|
| ORD ID | ord-469d597b28014aa2ae455cddbe8d012a |
|---|
| 출처 메모 | uspto-grants-1976_01 |
|---|
