2-Propenoyl chloride, 3-(3,4,5-trimethoxyphenyl)-, (2E)- → 5,6,13,13a-tetrahydro-2,3,11-trimethoxy-10-(3', 4', 5'-trimethoxycinnamoyloxy)-8H-dibenzo[a, g]quinolizine

Participants

Reaction Steps

1.9 g of 10-hydroxy-2,3,11-trimethoxy-5,6,13,13a-tetrahydro-8H-dibenzo[a, g]quinolizine hydrochloride was treated in the same manner as described in Example 6, using 2.0 g of 3,4,5-trimethoxycinnamoyl chloride and 20 ml of anhydrous pyridine and there was obtained 1.3 g (46.4% yield) of 5,6,13,13a-tetrahydro-2,3,11-trimethoxy-10-(3', 4', 5'-trimethoxycinnamoyloxy)-8H-dibenzo[a, g]quinolizine as a pale yellow powder. The methiodide derived from this compound was found to be in agreement with the methiodide of the compound obtained in Example 5 as determined from the melting point and IR spectrum.

Provenance & Evidence