Sodium Hydroxide → HCID 54064894, compound

Participants

Reaction Steps

The mixture of 0.9 g of 4-(4-acetamidophenylamino)-3-furfurylamino-5-sulfamoylbenzoic acid and 9 ml of 2N aqueous sodium hydroxide is refluxed for one hour under nitrogen, cooled, filtered and the filtrate acidified with glacial acetic acid to pH= 4-5. The precipitate formed is filtered off, washed with water and recrystallized from 50% aqueous ethanol, to yield the 4-(4-aminophenylamino)-3-furfurylamino-5-sulfamoylbenzoic acid melting at 232° with decomposition.

Provenance & Evidence