HCID 178509034, compound → 6-Methylthioguanine

HRID 1580918Notes

Reaction equation

HRID 1580918 reaction equation
S[C:2]1N=CN=C2C=1NC=N2.[NH2:11][C:12]1[N:20]=[C:19]2[C:15]([NH:16][CH:17]=[N:18]2)=[C:14]([SH:21])[N:13]=1>>[NH2:11][C:12]1[N:20]=[C:19]2[C:15]([NH:16][CH:17]=[N:18]2)=[C:14]([S:21][CH3:2])[N:13]=1

Participants

3

Reactant 2

HCID 178509034HCID 178509034, compoundHCID 178527888HCID 178527888, compound

Product 1

HCID 709766-Methylthioguanine

Procedure

By repeating this procedure but replacing the above 6-mercaptopurine compound with the corresponding 2-amino-6-mercaptopurine compound there is obtained the corresponding 2-amino-6-methylthiopurine compound.

Sources & evidence

ORD record
ord-5d0de43203604e288182babea0f0e25c
Source dataset
uspto-grants-1976_01
Patent number
US03935184

Reaction notes

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