HuagongsheHuagongshe Chemistry Print Report · For research reference only
Methanol → 4-[(1H-Imidazol-2-yl)sulfanyl]benzene-1,2-diamine
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Methanol | HCID 887 | — |
| Reactant | 5-[(1H-Imidazol-2-yl)sulfanyl]-2-nitroaniline | HCID 21482777 | — |
| Catalyst | Iron | HCID 23925 | — |
| Solvent | Water | HCID 962 | — |
| Product | 4-[(1H-Imidazol-2-yl)sulfanyl]benzene-1,2-diamine | HCID 21482783 | — |
Reaction Steps
A mixture of 2.6 g. of 2-amino-4-(imidazol-2-ylthio)-1-nitrobenzene, 2.6 g. of iron powder and 1.3 g. ferrous sulfate in 200 ml. methanol and 50 ml. water is refluxed for 2 hours. An additional 2.6 g. of iron is added and refluxing continued for 2 hours. The mixture is filtered and the filtrate stripped to yield 1,2-diamino-4-(imidazol-2-ylthio)benzene.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US03935209 |
| Source dataset | uspto-grants-1976_01 |
| ORD ID | ord-0bf9b626b795444ead2349b5c0181612 |
| Source note | uspto-grants-1976_01 |