Hydrochloric Acid → HCID 137220062, compound

Participants

Reaction Steps

23.4 G. of 1-ethyl-1,4,5,7-tetrahydro-3,4-dimethyl6H-pyrazolo[3,4-b]pyridin-6-one (0.12 mol.) are dissolved in 70 ml. of absolute ethanol while warming. After cooling, 32 ml. of ethereal hydrochloric acid (0.2 mol.HCl/l) are added to the solution. Two hours later, 100 ml. of absolute ether are added and the mixture is let stand overnight. The crystallized 1-ethyl-1,4,5,7-tetrahydro-3,4-dimethyl-6H-pyrazolo[3,4-b]pyridin-6-one, hydrochloride is filtered off and dried at 50°, yield 25.3 g. (92%), m.p. 192°-195° (dec.).

Provenance & Evidence