HCID 21560876, compound → HCID 21560961, compound

HRID 1580983Notes

Reaction equation

HRID 1580983 reaction equation
FC(F)(F)[C:3]1C=C[C:6]([C:9]2([OH:22])[C:17]3[C:12](=[CH:13][CH:14]=[CH:15][CH:16]=3)[C:11]3=[N:18][CH2:19][CH2:20][CH2:21][N:10]23)=[CH:5][CH:4]=1.FC(F)(F)C1C=CC=CC=1C1([OH:46])C2C(=CC=CC=2)C2=NCCCN12>>[O:46]1[CH:3]=[CH:4][CH:5]=[C:6]1[C:9]1([OH:22])[C:17]2[C:12](=[CH:13][CH:14]=[CH:15][CH:16]=2)[C:11]2=[N:18][CH2:19][CH2:20][CH2:21][N:10]12

Participants

3

Reactant 2

HCID 21560876HCID 21560876, compoundHCID 21560884HCID 21560884, compound

Product 1

HCID 21560961HCID 21560961, compound

Procedure

In a similar manner, 6-(4-trifluoromethylphenyl)-2,3,4,6-tetrahydropyrimido[2,1-a]isoindol-6-ol; 6-(2-trifluoromethylphenyl)-2,3,4,6-tetrahydropyrimido[2,1-a]isoindol-6-ol; and 6-furyl-2,3,4,6-tetrahydropyrimido[2,1-a]isoindol-6-ol are produced.

Sources & evidence

ORD record
ord-40ead371f8c849cdbf230e4b3a7a280c
Source dataset
uspto-grants-1976_01
Patent number
US03935218

Reaction notes

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