1-(3',4',5'-Trimethoxy benzyl)-2-phenyl piperazine → 1-(3',4',5'-Trimethoxy benzyl)-2-phenyl-4-diethylamino ethyl piperazine

HRID 1581012Notes

Reaction equation

HRID 1581012 reaction equation
[CH3:1][O:2][C:3]1[CH:4]=[C:5]([CH:19]=[C:20]([O:24][CH3:25])[C:21]=1[O:22][CH3:23])[CH2:6][N:7]1[CH2:12][CH2:11][NH:10][CH2:9][CH:8]1[C:13]1[CH:18]=[CH:17][CH:16]=[CH:15][CH:14]=1.[CH2:26](Cl)[CH3:27].[CH2:29]([NH:31][CH2:32][CH3:33])[CH3:30]>>[CH3:1][O:2][C:3]1[CH:4]=[C:5]([CH:19]=[C:20]([O:24][CH3:25])[C:21]=1[O:22][CH3:23])[CH2:6][N:7]1[CH2:12][CH2:11][N:10]([CH2:30][CH2:29][N:31]([CH2:26][CH3:27])[CH2:32][CH3:33])[CH2:9][CH:8]1[C:13]1[CH:18]=[CH:17][CH:16]=[CH:15][CH:14]=1

Participants

3

Reactant 2

HCID 214485551-(3',4',5'-Trimethoxy benzyl)-2-phenyl piperazineHCID 22641998Diethylamine ethylchloride

Product 1

HCID 867330251-(3',4',5'-Trimethoxy benzyl)-2-phenyl-4-diethylamino ethyl piperazine

Procedure

1-(3',4',5'-Trimethoxy benzyl)-2-phenyl piperazine prepared according to Example 17, is alkylated by means of diethylamine ethylchloride by following the procedure described in Example 3c. The resulting reaction product is obtained in the form of yellow oil boiling at 200° C./0.03 mm. Hg.

Workup

  1. customThe resulting reaction product

Sources & evidence

ORD record
ord-d7a3a4c7630246ac8e9a2e6a0cbfb5fa
Source dataset
uspto-grants-1976_01
Patent number
US03935214

Reaction notes

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