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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 15812Generated: October 25, 2026

Chlorophenyl isocyanate → N-(2-Chlorophenyl)-N'-(3-{2-[4-(2-methyl-5-quinolinyl)-1-piperazinyl]ethyl}phenyl)urea dihydrochloride

https://huagongshe.com/reaction/15812

Reaction equation

Participants

RoleNameHCIDCharge
ReactantChlorophenyl isocyanateHCID 76833—
Reactant3-(2-[4-(2-Methyl-5-quinolinyl)-1-piperazinyl]ethyl}anilineHCID 49852105—
ProductN-(2-Chlorophenyl)-N'-(3-{2-[4-(2-methyl-5-quinolinyl)-1-piperazinyl]ethyl}phenyl)urea dihydrochlorideHCID 5747830755%

Reaction Steps

The title compound was prepared in 55% yield according to the general procedure for the preparation of ureas (Method E) starting from 3-{2-[4-(2-methyl-5-quinolinyl)-1-piperazinyl]ethyl}aniline (D6) and 1-chloro-2-isocyanatobenzene.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07732600B2
Source datasetuspto-grants-2010_06
ORD IDord-9999ce0601984ef3b61236aa6a1cd105
Source noteuspto-grants-2010_06