Benzoic acid, 4-(acetyloxy)- → p-Acetoxybenzoyl chloride

HRID 1581446Notes

Reaction equation

HRID 1581446 reaction equation
[C:1]([O:4][C:5]1[CH:13]=[CH:12][C:8]([C:9](O)=[O:10])=[CH:7][CH:6]=1)(=[O:3])[CH3:2].S(Cl)([Cl:16])=O>>[C:1]([O:4][C:5]1[CH:13]=[CH:12][C:8]([C:9]([Cl:16])=[O:10])=[CH:7][CH:6]=1)(=[O:3])[CH3:2]

Participants

3

Reactant 2

HCID 16865Benzoic acid, 4-(acetyloxy)-HCID 24386Thionyl Chloride

Product 1

HCID 2756254p-Acetoxybenzoyl chloride

Procedure

100 Grams (0.555 mol) of 4-acetoxybenzoic acid was added to 400 g (3.36 mol) of thionyl chloride, and the mixture was refluxed under heat for 4 hours.

Workup

  1. temperaturethe mixture was refluxed
  2. temperatureunder heat for 4 hours

Sources & evidence

ORD record
ord-f063af5841c54b81911239dcda3a1a98
Source dataset
uspto-grants-2004_05
Patent number
US06730371B2

Reaction notes

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