Methylamine → HCID 23530181, compound

Participants

Reaction Steps

63 Grams (0.215 mol) of (R)-4-acetoxy-1-(3-ethyl-1-methylpentyloxycarbonyl)benzene was dissolved in 900 ml of dehydrated toluene, 25 g of a solution of 40% methylamine in methanol was dropwise added, and the mixture was stirred at room temperature for 5 hours. The reaction mixture was washed with 2N hydrochloric acid and washed with water. The resultant organic layer was dried over anhydrous sodium sulfate and filtered, and then the solvent was distilled off, to give 49 g (0.195 moll yield 91%) of an end compound.

Provenance & Evidence